BIOCHEMICAL STUDIES ON THE FIBRINOLYTIC ACTIVITY OF HEMOLYTIC STREPTOCOCCI

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Biochemical Studies on the Fibrinolytic Activity of Hemolytic Streptococci

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Broth cultures of hemolytic streptococci derived from patients are capable of rapidly liquefying normal human fibrin clot. The active fibrinolytic principle is also contained in sterile, cell-free filtrates of broth cultures. The degree of activity of filtrates parallels the activity of whole broth cultures sufficiently closely to indicate that large amounts of the fibrinolytic substance are fr...

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Biochemical Studies on the Fibrinolytic Activity of Hemolytic Streptococci I. Isolation and Characterization of Fibrinolysin by R. L. Garner,*

The fibrinolytic activity of hemolytic streptococci designates the capacity of cultures of the organisms to liquefy rapidly human fibrin clot (1). The lyric action is referable to the presence in the culture of an extracellular substance, characteristically elaborated by those strains of hemolytic streptococci which are derived from patients suffering with acute streptococcus infections. Invest...

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ژورنال

عنوان ژورنال: Journal of Experimental Medicine

سال: 1934

ISSN: 1540-9538,0022-1007

DOI: 10.1084/jem.60.2.239